Air pollution caused one in seven new cases of diabetes in 2016, according to a US study, which found even low levels raised the chances of developing the chronic disease.
Diabetes has primarily been associated with lifestyle factors like diet and a sedentary lifestyle, but research by the Washington University School of Medicine in St Louis said pollution also plays a major role.
The study estimated that pollution contributed to 3.2 million new diabetes cases globally in 2016 — or around 14 percent of all new diabetes cases globally that year.
“Our research shows a significant link between air pollution and diabetes globally,” said Ziyad Al-Aly, the study’s senior author.
Pollution is thought to reduce the body’s insulin production, “preventing the body from converting blood glucose into energy that the body needs to maintain health,” according to the research.
Al-Aly said the research, published in the Lancet Planetary Health, found an increased risk even with levels of air pollution currently considered safe by the US Environmental Protection Agency (EPA) and the World Health Organization (WHO).
Ballia (UP), June 10: Union Minister for Health and Family Welfare J P Nadda today claimed that the country will be free of leprosy this year and Kala-azar by next year.
The country will be free of leprosy this year and of Kala-azar by next year, he told reporters on the occasion of the inauguration of a hospital here.
To a question, Nadda said mortality rate in India has decreased and referred to a World Health Organisation report to stress that tetanus and some other diseases concerning children are well under control.
He claimed that Uttar Pradesh, which used to lag behind other states in the health sector, has taken a big leap ahead because of various schemes launched by the BJP government.
“The results of the schemes of the Centre can now be seen on the ground… the results of health schemes need some time to take shape,” Nadda said.
Geneva, Jun 8: The Democratic Republic of the Congo (DRC) has approved the use of five investigational therapeutics to treat Ebola virus disease (EVD), the World Health Organization (WHO) has said.
Four of the five approved drugs are currently in the country, which are Zmapp, GS-5734, REGN monoclonal antibody combination, and mAb114, under the framework of compassionate use and expanded access, China’s official new agency Xinhua quoted the WHO as saying.
Clinicians working in the treatment centers will make decisions on which drug to use as deemed helpful for their patients, and appropriate for the setting. The treatments can be used as long as informed consent is obtained from patients and protocols are followed, with close monitoring and reporting of any adverse events.
A woman with an aggressive form of breast cancer which defied chemotherapy and spread to other organs, was cured with an experimental treatment that triggered her immune system, researchers said Monday.
The woman has been cancer-free for two years, reported the US-based team, presenting their results as “a new immunotherapy approach” for the treatment of patients with a late-stage form of the disease.
Other experts not involved in the work hailed it as “exciting”.
So-called “immunotherapy” has already been shown to work in some people with cancer of the lung, cervix, blood cells (leukaemia), skin (melanoma) and bladder.
But an immune breakthrough for bowel, breast and ovary cancer has remained elusive.
In the latest study, a team extracted immune cells called lymphocytes from the patient, tweaked them in the lab, then reinjected them.
The woman was 49 when she signed up for the clinical trial after several attempts at a cure through conventional treatments had failed, said the study published in the scientific journal Nature Medicine.
The cancer had spread to various parts of her body, including the liver.
A person’s immune system is designed to kill invaders, including rogue, cancerous cells. But it can fail, often because it cannot recognise cancer cells containing the patient’s own DNA.
Immunotherapy trains a patient’s own immune cells to recognise and fight cancer.
For the new study, researchers took lymphocytes from a tumour in the woman’s body and scanned them for specific types which reacted to mutant, cancerous cells.
Kolkata, Jun 5 : Regular physical activity is proven to help prevent and treat
noncommunicable diseases (NCDs) such as heart disease, stroke, diabetes and
breast and colon cancer.
It also helps prevent hypertension, overweight and obesity and can improve
mental health, quality of life and well-being. Yet, much of the world is becoming
less active.
Physical activity is defined as any bodily movement produced by skeletal
muscles that requires energy expenditure. Regular moderate intensity physical
activity – such as walking, cycling, or participating in sports – has significant
benefits for health.
NCDs are responsible for 71 per cent of all deaths globally, including for the
deaths of 15 million people per year aged 30 to 70.
WHO has developed a new global action plan to help countries scale up policy
actions to promote physical activity. It responds to the requests by countries for
updated guidance, and a framework of effective and feasible policy actions to
increase physical activity at all levels.
Many of Member States have already started activities to promote physical
activity in their workplace and other areas, as well as taking “healthy breaks”
during the meetings.
The plan sets out four objectives and recommends 20 policy actions that are
applicable to all countries and address the cultural, environmental and individual
determinants of inactivity.
A key feature of this new plan is its call for a ‘’systems-based’’ approach where
effective implementation will require bold leadership combined with
cross-government and multisectoral partnerships at all levels to achieve a
coordinated, whole-of-system response.
Working in partnerships, WHO will support countries to implement a
whole-of-community approach to increase levels of physical activity in people
of all ages and abilities. Global, regional and national coordination and capacity
will be strengthened to respond to needs for technical support, innovation and
guidance.
WHO Director-General Dr Tedros Adhanom Ghebreyesus on Monday joining
Prime Minister António Costa of Portugal to launch the new “WHO Global action
plan on physical activity and health 2018-2030: More active people for a healthier
world.”
“Being active is critical for health. But in our modern world, this is becoming
more and more of a challenge, largely because our cities and communities aren’t
designed in the right ways,” said Dr Tedros. “We need leaders at all levels to help
people to take the healthier step. This works best at city level, where most
responsibility lies for creating healthier spaces.”
Worldwide, one in five adults, and four out of five adolescents (11-17 years), do
not do enough physical activity. Girls, women, older adults, poorer people, people
with disabilities and chronic diseases, marginalized populations, and indigenous
people have fewer opportunities to be active.
While the link between smoking and a range of cancers is well known, the World Health Organization warned Thursday there was too little awareness of tobacco’s impact on the human heart.
On the occasion of World No Tobacco Day Thursday, the UN health agency hailed that smoking had declined significantly since year 2000, but warned that there were still far too many people indulging in the dangerous habit.
And it cautioned that research showed there was “a serious lack of knowledge” about the different health risks associated with tobacco.
Tobacco use has been linked to more than seven million deaths worldwide each year, including some 890,000 from breathing in second-hand smoke.
But many people are unaware that nearly half of those deaths, around three million, are due to cardiovascular disease, including heart attacks and stroke, WHO warned.
“Most people know that using tobacco causes cancer and lung disease, but many people aren’t aware that tobacco also causes heart disease and stroke – the world’s leading killers,” WHO chief Tedros Adhanom Ghebreyesus said in a statement.
“Tobacco doesn’t just cause cancer. It quite literally breaks hearts,” he said.
Tobacco smoke contains more than 7,000 chemicals, including tar and others that can narrow arteries and damage blood vessels, and nicotine, which is associated with increases in heart rate and blood pressure.
At the same time, smoking unleashes poisonous gases like carbon monoxide, which replaces oxygen in the blood, thereby reducing the availability of oxygen for the heart muscle, WHO said.
The agency pointed out that tobacco use is responsible for around 17 percent of the nearly 18 million deaths from cardiovascular disease around the globe each year.
Yet in many countries, there is very low awareness that smoking significantly increases your chances of developing cardiovascular disease.
In China for instance, a large WHO survey showed that more than 60 percent of the population is unaware that smoking can cause heart attacks, while in India and Indonesia, more than half of adults are unaware that smoking can cause stroke.
“Governments have the power in their hands to protect their citizens from suffering needlessly from heart disease,” said Douglas Bettcher, who heads WHO’s non-communicable disease prevention unit.
According to a new WHO report on smoking trends and prevalence, the percentage of people worldwide who indulge in the habit has dropped from 27 percent in 2000 to 20 percent in 2016.
But it warned that the pace of reduction was too slow.
Due to population growth, the number of smokers in the world has remained relatively stable at around 1.1 billion, Bettcher told reporters.
Washington, May 26 : Proving the adage, ”You are, what your mother eats” correct beyond doubt, researchers from Oregon Health and Science University Hospital in Portland of Oregon have found the correlation between a mother’s nutrition habits and metabolism, which directly impacts the growth of her child.
In a study published online in Nature Communications, the research team, led by Jae W Lee, PhD, demonstrated that two neurons key to growth and metabolism – GHRH and AgRP – are developmentally interconnected.
Located in hypothalamus region of the brain, within a grouping of neurons known as the arcuate nucleus, GHRH, or growth hormone-release hormone, neurons orchestrate body growth and maturation. Meanwhile, AgRP, or Agouti-related peptide, neurons stimulate feeding and suppress energy usage.
According to Dr Lee, professor of pediatrics in the OHSU School of Medicine and OHSU Doernbecher Children’s Hospital, “We found that one specific protein called DLX1 is critical for GHRH neuron development. However, it also suppresses the development of AgRP neuron. When DLX1 was removed, the mouse’s growth was stunted, yet it appears obese.”
Additionally, DLX1 was found to suppress the development of OTP-labeled cells that become AgRP neurons. This would suggest normal growth development, but limited blockage of energy use, resulting in a trim figure.
“For the first time, these findings prove the intimate relationship between GHRH and AgRP neurons in developmental lineage. Further, the development of both neurons can be artificially preset in controlling postnatal growth,” Dr Lee told the Science Daily.
Washington, May 23: Watch out night shift staff!
Staying awake for work whole night can take a toll on your health as a new research published on Monday in the Proceedings of the National Academy of Sciences says it can disrupt levels and time of day patterns of more than 100 proteins in the blood.
Such proteins can influence blood sugar, energy metabolism, and immune function, according to the study.
The findings could open the door for developing new treatments for night shift workers, who make up about 20 per cent of the global workforce and are at higher risk for diabetes and cancer and also enable doctors to precisely time administration of drugs, vaccines and diagnostic tests around the circadian clock.
“This tells us that when we experience things like jet lag or a couple of nights of shift work, we very rapidly alter our normal physiology in a way that if sustained can be detrimental to our health,” said the paper’s senior author Kenneth Wright, director of the Sleep and Chronobiology Laboratory at University of Colorado Boulder.
The study is the first to examine how protein levels in human blood, also known as the plasma proteome, vary over a 24-hour period and how altered sleep and meal timing affects them, Chinese news agency Xinhua reported.
Kozhikode, May 23: Altogether 10 persons, out of the 12 contracted high fever caused by dreaded Nipah Virus (NiV), succumbed to the disease in this coastal district of Kerala during the last fortnight.
This was confirmed by state Health Minister KK Shyalaja on Tuesday quoting laboratory reports from National Virology Institute, Pune.
She told reporters that the lab reports also confirmed that Lini (31), staff nurse of Perambra Taluk Hospital, who tended three persons who died of the decease, also succumbed of the same virus.
She said lab reports also confirmed deaths of Koorachund native Rajan and Chekyad Ummathur Parakkadavu Thanttanatavida Ashokhan at Kochikode Medical College on Tuesday due to the same.
Eleven persons, including two, who were in a serious condition, were undergoing treatment in hospitals here, she said. Besides, two persons were undergoing treatment in Baby Memorial and Malabar Institute of Medical Sciences, reports said.
A high level team from the National Council for Disease Control (NCDC) New Delhi led by its Director Dr Sunset K Singh and Head of Epidemiology Dr S K Jain visited the affected areas in the district.
Geneva, May 17: Taking cognisance of more than 19 deaths caused due to the deadly Ebola virus in the Democratic Republic of Congo, the UN World Health Organisation on Thursday decided to convene an emergency committee meeting on Friday, to consider the international risks of an Ebola outbreak in DRC.
According to WHO Spokesman Christian Lindmeier, ‘The expert committee on Friday will decide whether to declare a ‘public health emergency of international concern’, which would trigger more international involvement, mobilising research and resources, local media reports said here.
India’s Universal Immunization Programme (UIP) on Sunday received a new addition —the Measles Rubella (MR) vaccination. The vaccine will replace the current two doses of measles vaccines given at 9-12 months and 16-24 months of age, and will offer dual protection, against measles and rubella.
The first phase of Measles Rubella (MR) vaccination campaign will begin in Karnataka, Tamil Nadu, Puducherry, Goa and Lakshadweep, covering nearly 3.6 crore target children. “This campaign will be taken up in a mission mode and has been rolled out in partnership with States, NGOs and development partners such as WHO, UNICEF, Gates Foundation, Lions Club, IPA, IMA. As part of a nationwide campaign, the health ministry will reach out to and cover 41 crore children, the largest ever in any campaign,” Faggan Singh Kulaste, Minister of State for Health and Family Welfare said.
“Children in the age group of 9 months to 15 years will be given a single shot of MR vaccination irrespective of their previous measles/rubella vaccination status or measles/rubella disease status,” he said. The vaccine will be provided free of cost across the States from session sites at schools and health facilities and outreach session sites.
“The vaccine protects against two deadly diseases—measles and rubella, only preventable through vaccination. There is no specific treatment for the diseases. MR vaccination is an essential investment by the government in children’s lives and will ensure that as future healthy citizens they contribute to the development of the country,” said Dr Yaron Wolman, Chief of Health, UNICEF India.
After the completion of the campaign, MR vaccine will be introduced in routine immunization and will replace measles vaccine, given at 9-12 months and 16-24 months of age of child. Measles is a deadly disease and one of the important causes of death in children. It is highly contagious and spreads through coughing and sneezing by an infected person. Measles can make a child vulnerable to life threatening complications such as pneumonia, diarrhoea and brain infection. Globally, in 2015, measles killed an estimated 1,34,200 children—mostly under the age of 5 years. In India, it killed an estimated 49,200 children.
Rubella is generally a mild infection, but has serious consequences if the infection occurs in pregnant women, causing congenital rubella syndrome (CRS), which is a cause of public health concern. CRS is characterised by congenital anomalies in the foetus and newborns affecting the eyes (glaucoma, cataract), ears (hearing loss), brain (microcephaly, mental retardation) and heart defects, causing a huge socio-economic burden on the families in particular and society in general.
“The measles disease burden was brought down by introduction of second dose of measles vaccine in 2010. For this introduction, supplementary immunization Activity (SIA) was conducted in 14 states (2010-13) with less than equal to 80 per cent measles coverage. The remaining states introduced measles second dose directly in routine immunization. However, those again need to be supplemented, and in order to further reduce the burden, the country is going to carry out the MR campaign,” said Dr Pradeep Haldar. Deputy Commissioner (Immunization), Union Health Ministry.